Obesity
Genomics and Pathophysiology
For many years, obesity has been attributed to an energy
imbalance in which energy intake exceeds energy expenditure. Positive energy balance, or a state in which energy intake surpasses energy expenditure, results in increased fat
stores in the body. Decreased fat stores results from energy
expenditure that is greater than energy intake (Bandini &
Flynn, 2003). Accumulation of fat stores has been explained
by several factors pertaining to excess fat deposits, adipose