Blocking D 2 can also produce such

Blocking D 2 can also produce such adverse
effects as the extrapyramidal side effects of dystonia,
parkinsonism, tardive dyskinesia, and akathisia.
However, other brain receptors (such as histamine,
serotonin, acetylcholine, and muscarinic) are also
implicated in the antipsychotic action of both typical
and atypical antipsychotics, giving rise to both
desired and adverse effects.
Atypical antipsychotics include such drugs as
clozapine, risperidone, olanzapine, quetiapine, and
aripiprazole. Specifically, the major adverse effects
of atypical antipsychotics can include weight gain,
glucose intolerance, elevation of blood lipids, and
cardiac abnormalities.
Thedifferentgroups ofadverseeffectsofatypical
antipsychotics can manifest as extrapyramidal,
anticholinergic, autonomic, psychic, hormonal,
and metabolic side effects. The metabolic effects
of antipsychotic medication treatment can result in
an increased risk for obesity and other changes,
demonstrating a potential between drug-induced
weight gain and risk for Type 2 diabetes, high-
lighting the possible risk for insulin resistance for
people who are treated with atypical antipsychotics
(Perez-Iglesias et al., 2007; Scheen & De Hert,
2007). Studies have found that the rate of obesity
among people living with psychotic disorders and
treated with antipsychotics is greater than that in the
general population (Coodin, 2001; Tschoner et al.,
2007). Research has further highlighted the equal
importance of the treatment of drug-induced meta-
bolic instability to reduce the risk for Type 2
diabetes and the actual treatment of psychosis.

Results (English) 3:

阻塞D 2也可以产生这种不良
影响肌张力障碍，
帕金森氏症，迟发性运动障碍，静坐不能的锥体外系副作用。
然而，大脑的其他受体（如作为组胺，
5-羟色胺，乙酰胆碱，和毒蕈碱）也
牵连的抗精神病作用典型、非典型抗精神病药物，从而产生所需的不良影响。

是非典型抗精神病药物包括利培酮，奥氮平，氯氮平
，喹硫平这样的药物，并
阿立哌唑。特别是，主要不利影响
非典型抗精神病药物可以包括重量增益，
葡萄糖不耐受，升高血脂，心脏异常
。
thedifferentgroups ofadverseeffectsofatypical
抗精神病药物，可以表现为锥体外系，
抗胆碱，自主，心理，激素，和代谢副作用。代谢的影响、抗精神病药物治疗可以导致
风险增加肥胖和其他变化，
演示一个潜在的药物、体重增加和风险型2糖尿病，高-
照明可能的风险胰岛素抵抗
的人谁是治疗非典型抗精神病药物
（佩雷斯伊格莱西亚斯等人。之间，2007；scheen&德赫尔，
2007）。研究发现，率的肥胖、人与人之间的生活与精神障碍、抗精神病药物治疗是大于
总人口（库丁，2001年；tschoner等人。，2007年
）。研究进一步强调了平等的重要性
治疗药物性元
代谢不稳定的风险降低2型
糖尿病与精神病的实际治疗。