OBJECTIVE:While symmetry and cluste

OBJECTIVE:

While symmetry and clustering of radiographic hand osteoarthritis (OA) have been described in middle-aged women, these have not been studied in elderly individuals and similar investigations are lacking for symptomatic hand OA. The goal of this study was to study patterns of joint involvement in symptomatic hand OA among elderly Caucasian men and women.
METHODS:

Using data from the Framingham Osteoarthritis Study, we defined a joint as having symptomatic OA if it had symptoms and radiographic OA (Kellgren and Lawrence grade > or =2). We assessed clustering of symptomatic OA using a chi(2)-test and evaluated the interrelationship of occurrence of symptomatic OA among different joints with generalized estimating equations.
RESULTS:

Of 976 subjects (age 71-99 yr, 36% men) examined, symptomatic OA more often affected multiple hand joints in an individual than would be expected by chance (P

Results (Indonesian) 1:

OBJECTIVE:While symmetry and clustering of radiographic hand osteoarthritis (OA) have been described in middle-aged women, these have not been studied in elderly individuals and similar investigations are lacking for symptomatic hand OA. The goal of this study was to study patterns of joint involvement in symptomatic hand OA among elderly Caucasian men and women.METHODS:Using data from the Framingham Osteoarthritis Study, we defined a joint as having symptomatic OA if it had symptoms and radiographic OA (Kellgren and Lawrence grade > or =2). We assessed clustering of symptomatic OA using a chi(2)-test and evaluated the interrelationship of occurrence of symptomatic OA among different joints with generalized estimating equations.RESULTS:Of 976 subjects (age 71-99 yr, 36% men) examined, symptomatic OA more often affected multiple hand joints in an individual than would be expected by chance (P<0.001). The presence of symptomatic OA at a particular joint was strongly associated with symptomatic OA in the same joint of the opposite hand, followed by other joints in the same row of the same hand, and then other joints in the same ray of the same hand. The symmetrical pattern of symptomatic OA was more apparent in women than in men.CONCLUSION:Our study demonstrates that symptomatic OA often affects multiple hand joints, and is more likely to cluster by row than by ray. The disease also occurs in a remarkably symmetrical pattern, especially in women.

Results (Indonesian) 2:

TUJUAN: Sementara simetri dan pengelompokan osteoarthritis tangan radiografi (OA) telah dijelaskan pada wanita paruh baya, ini belum diteliti pada orang tua dan penyelidikan serupa kurang untuk OA tangan gejala. Tujuan dari penelitian ini adalah untuk mempelajari pola keterlibatan bersama dalam OA tangan gejala antara pria Kaukasia tua dan wanita. METODE: Menggunakan data dari Framingham Osteoarthritis Studi, kita mendefinisikan sendi sebagai memiliki OA gejala jika memiliki gejala dan OA radiografi (Kellgren dan Lawrence kelas> atau = 2). Kami menilai pengelompokan OA gejala menggunakan chi (2) test dan mengevaluasi keterkaitan terjadinya OA gejala antara yang berbeda sendi dengan persamaan estimasi umum. HASIL: Dari 976 subyek (usia 71-99 tahun, 36% laki-laki) diperiksa, gejala OA lebih sering terkena beberapa sendi tangan dalam individu dari yang diharapkan secara kebetulan (P <0,001). Kehadiran OA gejala pada sendi tertentu sangat terkait dengan OA gejala pada sendi yang sama dari sisi yang berlawanan, diikuti oleh sendi lain di baris yang sama dari tangan yang sama, dan kemudian sendi lain di sinar yang sama dari tangan yang sama. Pola simetris dari gejala OA lebih jelas pada wanita dibandingkan pada pria. KESIMPULAN: Studi kami menunjukkan bahwa gejala OA sering mempengaruhi beberapa sendi tangan, dan lebih mungkin untuk cluster dengan baris daripada ray. Penyakit ini juga terjadi dalam pola yang sangat simetris, terutama pada wanita.