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phytosterols and triterpenoids (Abe et al. 1993). Oxidosqualenecyclases yielded one specific product, such aslupeol synthase (Shibuya et al. 1999; Guhling et al. 2006;Moses et al. 2013), b-amyrin synthase (Kushiro et al. 1998;Kirby et al. 2008; Shibuya et al. 2009) and a-amyrinsynthase (Muffler et al. 2011), cycloartenol synthase(Hayashi et al. 2000) and cucurbitadienol synthase (Shibuya2004). Following the formation of the carbon skeletons,the triterpene alcohols are modified by variouscytochrome P450s, dehydrogenases, reductases and other
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