APP undergoes posttranslational pro

APP undergoes posttranslational proteolytic processing by alpha-, beta-, and gamma-secretases. Alpha-secretase generates soluble amyloid protein, while beta- and gamma-secretases generate APP components with amyloidogenic features. These 2 processing pathways are mutually exclusive

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APP mengalami posttranslational proteolitik pengolahan oleh alpha, beta, dan gamma-secretases. Alfa-secretase menghasilkan protein amiloid larut, sementara secretases beta dan gamma menghasilkan komponen APP dengan fitur amyloidogenic. 2 ini pengolahan jalur saling eksklusif

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APP mengalami proses proteolitik posttranslational oleh alfa, beta, dan gamma-secretases. Alpha-secretase menghasilkan protein amiloid larut, sementara beta dan gamma-secretases menghasilkan komponen APP dengan fitur amyloidogenic. Ini 2 jalur pengolahan yang saling eksklusif

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