Abstract In the present study, an a

Abstract In the present study, an attempt has been made to validate the claimed uses of ‘Okra’
Hibiscus esculentus in liver diseases. The preventive action of ethanolic extract of okra (EEO)
against liver injury was evaluated in rodents using carbon tetrachloride-induced hepatotoxicity
model. EEO, at 250 and 500 mg/kg body weight, exerted significant dose-dependent hepatoprotection
by decreasing the CCl4-induced elevation of serum SGOT, SGPT, ALP, GGT, cholesterol,
triglycerides and malondialdehyde (MDA) non-protein sulfhydryls (NP-SH) and total protein
(TP) levels in the liver tissue. A significant reduction was also observed in pentobarbital-induced
sleeping time in mice. The hepatoprotective and antioxidant activities of the extract are being comparable
to standard silymarin. These findings were supported by histological assessment of the liver
biopsy. The ability of okra extract to protect chemically induced liver damage may be attributed to
its potent antioxidant property.

Results (English) 3:

摘要：在本研究中，已尝试验证声称使用“秋葵”木槿在肝脏疾病。黄秋葵的乙醇提取物的预防措施（EEO）抗肝损伤在使用四氯化碳诱导的肝毒性的啮齿类动物的评价模型。生态，在250和500毫克/公斤体重，产生了显著的剂量依赖性的保护作用通过降低CCl4诱导的血清谷草转氨酶、谷丙转氨酶、ALP、GGT升高，胆固醇，甘油三酯和丙二醛（MDA）的非蛋白巯基（NP-SH）和总蛋白（茶多酚）在肝组织中的含量。在戊巴比妥钠诱导的也观察到一个显着减少小鼠睡眠时间。该提取物的保肝和抗氧化活性是可比标准的水飞蓟素。这些研究结果支持肝组织学评估活检.黄秋葵提取物保护化学性肝损伤可能归因于能力其强大的抗氧化性能。