Act mainly in the distal tubule to

Act mainly in the distal tubule to decrease the reabsorption of Na+ by inhibition of a Na+/Cl- cotransporter on the luminal membrane of the distal convoluted tubule
increase the concentration of Na+ and Cl- in the tubular fluid
Contoh: HCT, Chlorthiazide

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Undang-undang terutama di tubulus distal untuk mengurangi reabsorpsi Na + oleh penghambatan Na +/ Cl-cotransporter pada membran luminal dari tubulus berbelit-belit distalmeningkatkan konsentrasi Na + dan Cl - dalam cairan tabungContoh: HCT, Chlorthiazide

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