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ResultsIn all, 158 breast cancer patients were recruited into thestudy and 55 patients developed seroma, giving an overallincidence of 35% for seroma formation after breast surgery. The mean age of patients was 46.3 years (SD ± 11.9).One hundred and fifteen patients (73%) underwent MRMand BP was performed in 43 patients (27%). The axillarynode involvement was significantly different betweenMRM and BP patients (χ2 = 4.52, df = 1, P = 0.03) indicatingthat those who underwent MRM had higher rate ofpositive axillary nodes compared to those who receivedBP (78% vs. 21% respectively). Thirty-one mastectomieswere performed by scalpel dissection of the skin flap(20%) and 127 by cautery dissection (80%). Two closedsuction drains were placed in all patients undergoing surgery.Sixty-six percent of patients (n = 104) were node positiveand the remaining 34% (n = 54) were node negative.The patients' characteristics and univariate odds ratios areshown in Table 1.The results of multivariate logistic regression analysisindicated that only the surgical type was significantly associatedwith seroma formation (OR = 2.83, 95% CI 1.01–7.90, P = 0.04). Of patients with BP, 10 of 43 (23%) developedseroma, while those who underwent MRM 45 of 115(39%) developed seroma. The seroma formation did notshow any significant association with any other variablesstudied. The results of maultivariate analysis are shown inTable 2.
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