(1) (a) What is the critical path i

(1) (a) What is the critical path in drug development? (b) List the main stages in
the critical path of the development of a drug.
(2) Explain the meaning of the terms (a) dosage form, (b) ELF, (c) telescoping in
drug production, (d) excipient and (e) double blind trial.
(3) Outline the chemical factors that need to be considered when scaling up a
research synthesis to pilot plant scale.
(4) Outline a possible production scale route for the preparation of the thromboxane analogue A.
(5) Explain the differences between (a) preclinical and clinical trials and (b) Phase
I and Phase II trials.
(6) What is a patent? Why is it necessary to patent drugs?

Results (English) 3:

（1）（a）药物开发的关键路径是什么？（b）列出的主要阶段药物开发的关键路径。（2）解释术语（一）剂型，（b）（c）中的小精灵，伸缩药品的生产、（D）和（E）作双盲试验。（3）概述了在结垢时需要考虑的化学因素中试规模的合成研究。（4）纲要血栓素类似物的制备路线可能的生产规模（5）解释（a）临床前和临床试验及（b）期的差异I和II期临床试验。（6）什么是专利？为什么有必要专利药物？