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Genomics, nutrition, obesity, and diabetes.
Authors:
Johnson RL; Williams SM; Spruill IJ
Affiliation:
Assistant Professor, School of Nursing, Vanderbilt University, School of Nursing, Godchaux Hall, Nashville, TN 37240, rolanda.johnson@vanderbilt.edu
Source:
Journal of Nursing Scholarship (J NURS SCHOLARSH), 2006 1st Quarter; 38 (1): 11-8. (47 ref)
Publication Type:
journal article - review, tables/charts
Language:
English
Major Subjects:
Diabetes Mellitus
Genomics
Nutrition
Obesity
Minor Subjects:
Diabetes Mellitus -- Diet Therapy; Diabetes Mellitus -- Epidemiology; Diabetes Mellitus -- Physiopathology; Diabetes Mellitus -- Risk Factors; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Supplementation; Environment; Genetic Counseling; Genetic Screening; Genotype; Mutation; Nursing Role; Obesity -- Physiopathology; Phenotype
Abstract:
Purpose: To present evidence of genetic and environmental interactions as they relate to nutrition, diabetes, and obesity. Methods: A review of seminal literature related to genetics, obesity, and diabetes. Findings: Multifactorial interactions are important in the development of nutrition-related disorders, but the challenge remains to explain how these interactions are expressed. Treating subpopulations of people might be important and useful to some extent at present, but in the future treating people of given genetic predispositions and other personal and environmental factors will have greater effects on quality-of-life indicators and life expectancies. Conclusions: Individualization coupled with multifactorial interactions will lead to new and more effective preventive and treatment modalities of nutrition-related disorders. With obesity and diabetes, genomics will bridge the traditional use of diet, exercise, and weight reduction with other environmental factors, ultimately leading to healthier lives.
Journal Subset:
Core Nursing; Double Blind Peer Reviewed; Expert Peer Reviewed; Nursing; Online/Print; Peer Reviewed; USA
Special Interest:
Nutrition
ISSN:
1527-6546
MEDLINE Info:
PMID: 16579318 NLM UID: 100911591
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