ABSTRACTThe present investigation w

ABSTRACT
The present investigation was undertaken with an objective of formulating modified
release (MR) matrix tablets of Oxcarbazepine (OXC) an anti-epileptic drug, based on cellulose
ether polymers like Hydroxy Propyl Methyl Cellulose (HPMC K4M and LVCR 100) and
Hydroxy Propyl Cellulose (HPC JF) as drug release retardants to overcome poor patient
compliance and exposure to high doses associated with currently marketed immediate release
(IR) dosage forms. The tablets were prepared by direct compression process and evaluated for
various physico- chemical/mechanical parameters.

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Results (Indonesian) 1: [Copy]

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ABSTRACTThe present investigation was undertaken with an objective of formulating modifiedrelease (MR) matrix tablets of Oxcarbazepine (OXC) an anti-epileptic drug, based on celluloseether polymers like Hydroxy Propyl Methyl Cellulose (HPMC K4M and LVCR 100) andHydroxy Propyl Cellulose (HPC JF) as drug release retardants to overcome poor patientcompliance and exposure to high doses associated with currently marketed immediate release(IR) dosage forms. The tablets were prepared by direct compression process and evaluated forvarious physico- chemical/mechanical parameters.

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Results (Indonesian) 2:[Copy]

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ABSTRAK
Penyelidikan ini dilakukan dengan tujuan merumuskan modifikasi
release (MR) tablet matriks oxcarbazepine (OXC) obat anti-epilepsi, berdasarkan selulosa
polimer eter seperti Hydroxy Propyl Methyl Cellulose (HPMC K4M dan LVCR 100) dan
Hidroksi propil selulosa (HPC JF) sebagai retardants pelepasan obat untuk mengatasi pasien miskin
kepatuhan dan paparan dosis tinggi yang terkait dengan saat ini dipasarkan pembebasan segera
bentuk sediaan (IR). Tablet dibuat dengan proses kompresi langsung dan dievaluasi untuk
berbagai bahan kimia / parameter mekanik psiko.

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Results (Indonesian) 3:[Copy]

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