The Thai genome individuals have a predicted significantly increase highest risk for response to hepatitis c treatment is twenty-seven fold, have a predicted risk that for skin pigmentation is twelve fold, Testicular germ cell tumor is eight fold, hypokalemic periodic paralysis is fivefold and this model has a predicted diseases risk is twofold, include age-related macular degeneration, alopecia areata, psoriasis, esophageal cancer, blue vs. green eyes and blond vs. brown hair color, longevity, beta thalassemia/hemoglobin E disease, chronic hepatitis c infection.