Vancomycin inhibits synthesis of ba

Vancomycin inhibits synthesis of bacterial cell wall phospholipids as well as peptidoglycan polymerization by binding to the D-Ala-D-Ala side chain of the precursor pentapeptide.
This prevents the transglycosylation step in peptidoglycan polymerization, thus weakening the cell wall and damaging the underlying cell membrane.

Daptomycin induces rapid depolarization of the membrane, thus disrupting multiple aspects of membrane function and inhibiting intracellular synthesis of DNA, RNA, and protein

Results (Indonesian) 2:

Vankomisin menghambat sintesis bakteri fosfolipid dinding sel serta polimerisasi peptidoglikan dengan mengikat D-Ala-D-Ala rantai sisi pentapeptide prekursor.
Hal ini untuk mencegah langkah transglycosylation dalam polimerisasi peptidoglikan, sehingga melemahkan dinding sel dan merusak membran sel yang mendasari.

Daptomycin menginduksi depolarisasi cepat membran, sehingga mengganggu beberapa aspek fungsi membran dan menghambat sintesis intraseluler DNA, RNA, dan protein