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the impact of molecular biology and other new technologies?In the new millennium, molecular biology is having a significant impact on drug discovery, offering us over 30 000 genes and their protein products as potential drug targets, and revolutionizing the processes involved in seeking drug targets, testing hypotheses and screening for activity. In addition, the techniques of combinatorial chemistry are available, which generate thousands of compounds to test against the thousands of targets, as are the computer programs that can analyse the millions of data points that will result. What role can there be for in vivo pharmacology in this ‘Brave New Post-Genomic World’?
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