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Biomedical and dental applications of titanium and its alloys are
constantly increasing because of their high biotolerance, high corrosion
resistance, and a good balance of mechanical properties,
such as light weight as compared with other metallic materials.
A thin, dense, protective oxide layer (mainly TiO2) forms rapidly
on the Ti surface when exposed to the atmosphere. This produces
excellent anti-corrosive and biocompatibility properties. However,
titanium and its alloys exhibit poor osteoinductive properties [1].
As a result, these materials and the means to optimize their biocompatibility
have been extensively studied over the past decades
[2–4]. To improve orthopedic implant integration with the surrounding
bone, various surface treatments for the topographic
and chemical modification of titanium have been attempted. These
include blasting, wet chemical etching, porous-sintering, anodization,
plasma-spraying, hydroxyapatite coating, incorporation of
ions in the titanium oxide, and a combination of these [5]. Among
the various advanced methods for improving the interface properties
and life span of a Ti-based implant [6–8], anodization methods
have attracted great attention because of their controllable, reproducible
results as well as the simple process [9–11]. But, anodization
parameters greatly influence the surface micromorphology,
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