The nucleoid was described with res

The nucleoid was described with respect to chromosome segregation above. Indeed, experiments in many of the model systems indicate that bacteria carefully coordinate the position of the chromosome in the cell. Through techniques in which individual positions in the chromosome can be localized in whole cells, it has been shown that genes are localized in the cell in roughly the same order as one would presume by looking at the DNA sequence. A variety of techniques are providing insight into how the structure of the chromosome is maintained in the cell. The molecular mechanisms that maintain the chromosome structure remain a mystery, but specificsystems are likely to exist to ensure that the chromosome is available for transcription, recombination, and other functions. Bacterial nucleoids can be released from cells in a relatively intact state using gentle lysis procedures. DNA isolated from bacteria by such a procedure is shown in Figure 1.24. The nucleoid is composed of 30 to 50 loops of DNA emerging from a more condensed region, or core. Seeing this tangle of loops, it is difficult to imaginethat the DNA in this complicated structure is actually one long, continuous circular molecule.

Results (English) 1:

The nucleoid was described with respect to chromosome segregation above. Indeed, experiments in many of the model systems indicate that bacteria carefully coordinate the position of the chromosome in the cell. Through techniques in which individual positions in the chromosome can be localized in whole cells, it has been shown that genes are localized in the cell in roughly the same order as one would presume by looking at the DNA sequence. A variety of techniques are providing insight into how the structure of the chromosome is maintained in the cell. The molecular mechanisms that maintain the chromosome structure remain a mystery, but specific
systems are likely to exist to ensure that the chromosome is available for transcription, recombination, and other functions. Bacterial nucleoids can be released from cells in a relatively intact state using gentle lysis procedures. DNA isolated from bacteria by such a procedure is shown in Figure 1.24. The nucleoid is composed of 30 to 50 loops of DNA emerging from a more condensed region, or core. Seeing this tangle of loops, it is difficult to imagine
that the DNA in this complicated structure is actually one long, continuous circular molecule.

Results (English) 3:

核仁是根据染色体分离来描述的。事实上，在许多模型系统中的实验表明，细菌仔细地协调染色体在细胞中的位置。通过将染色体上的个别位置定位在整个细胞中的技术，已经证明基因在细胞中的定位顺序与通过观察DNA序列所推测的顺序大致相同。各种各样的技术提供了对染色体结构如何在细胞中维持的洞察。维持染色体结构的分子机制仍然是一个谜，但却是特殊的
系统可能存在，以确保染色体可用于转录、重组和其他功能。通过温和的裂解过程，细菌核仁可以相对完整地从细胞中释放出来。通过这种方法从细菌中分离出的DNA如图1.24所示。核仁是由30到50个DNA环组成的，这些DNA环是从一个更浓缩的区域或核心出现的。看到这些错综复杂的循环，很难想象
这个复杂结构中的DNA实际上是一个长而连续的环状分子。