Chimeric Antibodies :•Thegenescodin

Chimeric Antibodies :
•Thegenescodingforthemurinevariableregionofheavyandlightchainsareisolatedfromthehybridomaandamplifiedbypolymerasechainreaction(PCR).
•Constant-regiongenesofhumanheavyandlightchainsalsoareamplified.
•Afterinsertionofhumanandmurinegenesintoaplasmidandtransfectionintobacteria,chimericantibodiesareproducedasinclusionbodies.
•Followinglysisofthecells,thechimericantibodiesarepurifiedforinvivouse.
•Antibodyaggregationandlimitedgrowthofantibody-producingbacteriarestricttheusefulnessofbacterialexpressionsystems.
Humanized Antibodies
Human Monoclonal Antibodies

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Chimeric antibodi:•Thegenescodingforthemurinevariableregionofheavyandlightchainsareisolatedfromthehybridomaandamplifiedbypolymerasechainreaction(PCR).•Constant-regiongenesofhumanheavyandlightchainsalsoareamplified.•Afterinsertionofhumanandmurinegenesintoaplasmidandtransfectionintobacteria, chimericantibodiesareproducedasinclusionbodies.•Followinglysisofthecells, thechimericantibodiesarepurifiedforinvivouse.•Antibodyaggregationandlimitedgrowthofantibody-producingbacteriarestricttheusefulnessofbacterialexpressionsystems.Antibodi HumanizedAntibodi monoklonal Human

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Results (Indonesian) 2:[Copy]

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Chimeric Antibodi:
• Thegenescodingforthemurinevariableregionofheavyandlightchainsareisolatedfromthehybridomaandamplifiedbypolymerasechainreaction (PCR).
• Constant-regiongenesofhumanheavyandlightchainsalsoareamplified.
• Afterinsertionofhumanandmurinegenesintoaplasmidandtransfectionintobacteria, chimericantibodiesareproducedasinclusionbodies.
• Followinglysisofthecells, thechimericantibodiesarepurifiedforinvivouse.
• Antibodyaggregationandlimitedgrowthofantibody-producingbacteriarestricttheusefulnessofbacterialexpressionsystems.
Humanized Antibodi
Human Antibodi Monoklonal

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Results (Indonesian) 3:[Copy]

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