Disease relevance of CDK3Retinoic a

Disease relevance of CDK3
Retinoic acid-mediated G1 arrest is associated with induction of p27(Kip1) and inhibition of cyclin-dependent kinase 3 in human lung squamous carcinoma CH27 cells [1].
Among them are binding by the retinoblastoma gene product (pRb), activation by cdk3, and S-phase-dependent down-regulation of DNA-binding capacity by cyclin A-dependent kinase [2].

Results (Indonesian) 2:

Relevansi penyakit CDK3
retinoat asam-dimediasi penangkapan G1 dikaitkan dengan induksi p27 (Kip1) dan penghambatan cyclin-dependent kinase 3 di paru-paru manusia sel karsinoma skuamosa CH27 [1].
Di antara mereka mengikat dengan produk gen retinoblastoma (PRB) , aktivasi oleh cdk3, dan S-fase tergantung down-regulasi kapasitas DNA-binding oleh cyclin A-dependent kinase [2].