Drug excipients compatibility by FT

Drug excipients compatibility by FT-IR spectroscopy
The FT-IR spectra of pure drug and OXC with different
excipients like HPMC K4M, HPMC LVCR 100, HPC JF, Avicel
PH 105, Avicel PH 101, PGS, FlowLac, DCP, SLS, PEG 6000, β-
CD and HP- β- CD was measured using ATR-FTIR
spectrophotometer (Bruker, Germany). ATR spectra were
measured over the wave number range of 4000-500 cm-1 at a
resolution of 1.0 cm-1. The powder or film sample is simply placed
onto the ATR crystal and the sample spectrum is collected.

Results (Indonesian) 2:

Eksipien obat kompatibilitas dengan spektroskopi FT-IR
The FT-IR spektrum obat murni dan OXC dengan berbagai
bahan pengisi seperti HPMC K4M, HPMC LVCR 100, HPC JF, Avicel
PH 105, Avicel PH 101, PGS, FlowLac, DCP, SLS, PEG 6000 , β-
CD dan CD HP β- diukur dengan menggunakan ATR-FTIR
spektrofotometer (Bruker, Jerman). ATR spektrum yang
diukur selama rentang bilangan gelombang 4000-500 cm-1 pada
resolusi 1,0 cm-1. Bubuk atau film sampel hanya ditempatkan
ke kristal ATR dan spektrum sampel dikumpulkan.